Prof. Luigi Fontana is a physician-scientist and Professor of Medicine, internationally recognized for his work on human longevity, dietary restriction, metabolic health and the biology of healthy aging. For more than two decades, he has led clinical and translational research on how nutrition, metabolism, inflammation and lifestyle shape healthspan and chronic disease risk. His focus is on what actually works in humans, not on speculative longevity narratives or hype-driven interventions. His work has been published in journals including Science, Cell, NEJM, JAMA and The BMJ.